Disclosed are carriers for drugs and/or MR imaging agents having a lipid bilayer shell comprising a phospholipid having two terminal alkyl chains, one being a short chain having a chain length of at most fourteen carbon atoms, the other being a long chain having a chain length of at least fifteen carbon atoms. The mixed long/short chain phospholipids serve to tune the release properties of the carrier. Preferred phospholipids are phosphatidylcho lines.
申请公布号
EP2593086(A1)
申请公布日期
2013.05.22
申请号
EP20110744084
申请日期
2011.07.08
申请人
KONINKLIJKE PHILIPS ELECTRONICS N.V.
发明人
LANGEREIS, SANDER;GRUELL, HOLGER;DE SMET, MARISKA;AUSSEMS-CUSTERS, ERICA, MARIA, GERARDA;LUB, JOHAN