发明名称 ANTIBODY GLYCOSYLATION VARIANTS
摘要 Antibody and other Fc-containing molecules with glycosylation variations in the Fc region show increased resistance to proteases, such as pepsin, plasmin, trypsin, chymotrypsin, a matrix metalloproteinase, a serine endopeptidase, and a cysteine protease. The Fc-containing molecules are useful in the treatment of various diseases and disorders.
申请公布号 EP2494061(A4) 申请公布日期 2013.05.22
申请号 EP20100830418 申请日期 2010.10.25
申请人 JANSSEN BIOTECH, INC. 发明人 LUO, JINQUAN;MCCARTHY, STEPHEN;RAJU, T., SHANTHA;SCALLON, BERNARD;SPINKA-DOMS, TRACY
分类号 C07K16/00 主分类号 C07K16/00
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