发明名称 |
HETEROCYCLIC COMPOUND, AND p27 KIP1 DEGRADATION INHIBITOR |
摘要 |
<p>A novel heterocyclic compound or a salt thereof useful for selectively inhibiting the degradation of p27 kip1 is provided. The compound or the salt thereof is represented by the following formula (1):
wherein A represents an alkyl group, a cycloalkyl group, an aryl group or a heterocyclic group, the group A may have a substituent; the ring B represents a 5- to 8-membered monocyclic heterocyclic ring or a condensed ring containing the monocyclic heterocyclic ring, the ring B may have a substituent; the ring C represents an aromatic ring, the ring C may have a substituent; L represents a linker comprising a main chain having 3 to 5 atoms selected from the group consisting of a carbon atom, a nitrogen atom, an oxygen atom and a sulfur atom, wherein at least one atom in the main chain is a hetero atom selected from the group consisting of a nitrogen atom, an oxygen atom and a sulfur atom, the linker L may have a substituent; and n is 0 or 1.</p> |
申请公布号 |
EP2594555(A1) |
申请公布日期 |
2013.05.22 |
申请号 |
EP20110800989 |
申请日期 |
2011.07.01 |
申请人 |
ASKA PHARMACEUTICAL CO., LTD. |
发明人 |
UCHIDA, HIROSHI;ASAGARASU, AKIRA;MATSUI, TERUAKI |
分类号 |
C07D207/34;A61K31/341;A61K31/415;A61K31/4178;A61K31/426;A61K31/427;A61K31/437;A61K31/498;A61K31/5383;A61K31/55;A61P3/10;A61P29/00;A61P35/00;A61P43/00;C07D231/40;C07D277/20;C07D277/42;C07D307/68;C07D403/12;C07D405/14 |
主分类号 |
C07D207/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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