发明名称 |
Triazolyl pyridyl benzenesulfonamides |
摘要 |
Compounds are provided that act as potent antagonists of the CCR2 or CCR9 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR2 and CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases, CCR9-mediated diseases, as controls in assays for the identification of CCR2 antagonists and as controls in assays for the identification of CCR9 antagonists.
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申请公布号 |
US8445518(B2) |
申请公布日期 |
2013.05.21 |
申请号 |
US20100708900 |
申请日期 |
2010.02.19 |
申请人 |
CHARVAT TREVOR T.;HU CHENG;JIN JEFF;LI YANDONG;MELIKIAN ANITA;PENNELL ANDREW M. K.;PUNNA SREENIVAS;UNGASHE SOLOMON;ZENG YIBIN;CHEMOCENTRYX, INC. |
发明人 |
CHARVAT TREVOR T.;HU CHENG;JIN JEFF;LI YANDONG;MELIKIAN ANITA;PENNELL ANDREW M. K.;PUNNA SREENIVAS;UNGASHE SOLOMON;ZENG YIBIN |
分类号 |
A61K31/4439;C07D401/00 |
主分类号 |
A61K31/4439 |
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地址 |
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