| 发明名称 |
Thieno- and furo-pyrimidine modulators of the histamine H4 receptor |
| 摘要 |
Thieno- and furo-pyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the modulation of histamine H4 receptor activity and for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as inflammation.
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| 申请公布号 |
US8445482(B2) |
申请公布日期 |
2013.05.21 |
| 申请号 |
US201213456174 |
申请日期 |
2012.04.25 |
| 申请人 |
EDWARDS JAMES P.;NEFF DANIELLE K.;SMITH DEBORAH M.;VENABLE JENNIFER D.;JANSSEN PHARMACEUTICA NV |
发明人 |
EDWARDS JAMES P.;NEFF DANIELLE K.;SMITH DEBORAH M.;VENABLE JENNIFER D. |
| 分类号 |
C07D243/08;A61K31/501;A61K31/5025;A61K31/519;A61K31/5513;A61P29/00;C07D491/147 |
主分类号 |
C07D243/08 |
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