发明名称 |
IMMUNIZING COMPOSITION AND METHOD FOR INDUCING AN IMMUNE RESPONSE AGAINST THE .BETA.-SECRETASE CLEAVAGE SITE OF AMYLOID PRECURSOR PROTEIN |
摘要 |
The present invention is directed to an immunizing composition containing an antigenic product such as a multiple antigen peptide system (MAPS) or a filamentous bacteriophage displaying an A.beta.PP epitope spanning the .beta.-secretase cleavage site of A.beta.PP and a method for inducing an immune response against the .beta.-secretase cleavage site of A.beta.PP using this immunizing composition. The present invention is also directed to antibodies against the .beta.-secretase cleavage site of A.beta.PP and their use in a method for inhibiting the formation of amyloid .beta..
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申请公布号 |
CA2477675(C) |
申请公布日期 |
2013.05.21 |
申请号 |
CA20032477675 |
申请日期 |
2003.03.04 |
申请人 |
RAMOT AT TEL-AVIV UNIVERSITY LTD. |
发明人 |
SOLOMON, BEKA |
分类号 |
A61K9/127;A61K38/00;A61K38/04;A61K39/00;A61K39/385;A61K39/39;A61K39/395;A61K39/40;A61K39/42;A61P25/28;A61P37/04;C07K7/06;C07K14/47;C07K16/00;C07K16/18 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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