| 发明名称 |
Biomolecular coating for implants |
| 摘要 |
Methods and compositions are provided for improving tissue growth and device integration in vivo. Substrates and devices coated with an alpha2beta1 or alpha5beta1 integrin-specific ligand are provided. The substrates and devices coated with an alpha2beta1 or alpha5beta1 integrin-specific ligand are shown to have greater tissue formation on the surface relative to controls, in particular greater bone formation.
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| 申请公布号 |
US8445006(B2) |
申请公布日期 |
2013.05.21 |
| 申请号 |
US201213372234 |
申请日期 |
2012.02.13 |
| 申请人 |
GARCIA ANDRES J.;REYES CATHERINE D.;PETRIE TIMOTHY;SCHWARTZ ZVI;BOYAN BARBARA;RAYNOR JENNY E.;COLLARD DAVID M.;WOJTOWICZ ABIGAIL M.;GULDBERG ROBERT E.;GEORGIA TECH RESEARCH CORPORATION |
发明人 |
GARCIA ANDRES J.;REYES CATHERINE D.;PETRIE TIMOTHY;SCHWARTZ ZVI;BOYAN BARBARA;RAYNOR JENNY E.;COLLARD DAVID M.;WOJTOWICZ ABIGAIL M.;GULDBERG ROBERT E. |
| 分类号 |
A61F2/00;A61K38/00;A61K51/00;C07K2/00;C07K4/00;C07K5/00;C07K7/00;C07K9/00;C07K16/00;C07K17/00 |
主分类号 |
A61F2/00 |
| 代理机构 |
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