发明名称 PREPARATIONS OF SINGLE DOMAIN ANTIGEN-BINDING MOLECULES
摘要 FIELD: medicine, pharmaceutics.SUBSTANCE: invention relates to field of biotechnology and immunology. Claimed is medication for treatment and prevention of TNF-dependent disorder, which contains molecule of TNF-binding nanobody, lyoprotector, surface-active substance and buffer, method of such medication obtaining, method of lyophilised preparation reduction and method of analysis of medication-manufacturing process, as well as method and set for treatment or prevention of TNF-dependent disorder.EFFECT: invention ensures obtaining stable pharmaceutical preparations of TNF-binding nanobodies and can be applied in therapy of TNF-dependent diseases.30 cl, 12 ex, 3 tbl, 32 dwg
申请公布号 RU2481824(C2) 申请公布日期 2013.05.20
申请号 RU20110113438 申请日期 2009.10.29
申请人 ABLINKS N.V 发明人 FERNANDES DZHEJSON E.;DIKSON DEHNIEL' A.;PAULSON ANDREA
分类号 A61K9/19;A61K9/08;A61K39/395;A61P19/00;A61P29/00;A61P35/00;A61P37/00;C07K16/24 主分类号 A61K9/19
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