发明名称 |
SCREENING METHOD OF MATERIALS FOR REGULATING PIGMENTATION OF SKIN |
摘要 |
PURPOSE: A method for screening a material which regulates skin pigmentation is provided to screen a material for regulating skin pigmentation, and to effectively treat hyperpigmentation or hypopigmentation by regulating intracellular and intercellular signal transduction faction and transcription factor. CONSTITUTION: A method for screening a material which regulates skin pigmentation comprises: a step of treating one or more gene selected from the group consisting of IFN gamma, IL4, IL17, IL6, STAT3, STAT6, JAK1, JAK2, and JAK3 with a candidate material; and a step of selecting a candidate material which enhances or reduces gene expression as a material which regulates skin pigmentation. A candidate material which enhances gene expression is selected as a useful material which possibly suppresses pigmentation. A candidate material which reduces gene expression is selected as a useful material which possibly enhances skin pigmentation. [Reference numerals] (AA) Comparative example; (BB) Example 1; (CC) Example 2; (DD) Example 3
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申请公布号 |
KR20130051353(A) |
申请公布日期 |
2013.05.20 |
申请号 |
KR20110116647 |
申请日期 |
2011.11.09 |
申请人 |
AMOREPACIFIC CORPORATION |
发明人 |
CHOI, HYUN JUNG;CHOI, HYUN;HAN, JI YEON;PARK, JU YEARL;SHIN, DONG WOOK;LEE, TAE RYONG;NOH, MIN SOO;KIM, KWANG MI |
分类号 |
G01N33/68;C12N15/115;G01N33/15;G01N33/53 |
主分类号 |
G01N33/68 |
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