摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for producing an N-acylamino acid (3) in good yield. <P>SOLUTION: The method is configured to produce an N-acylamino acid (3) by reacting an aldehyde compound (1), an amide compound (2), and carbon monoxide in the presence of a cobalt compound and hydrogen in a solvent in a reactor. The aldehyde compound (1), the amide compound (2) and the solvent are supplied into the reactor in which the solvent, the cobalt compound, hydrogen and carbon monoxide have been placed in advance. <P>COPYRIGHT: (C)2013,JPO&INPIT |