| 发明名称 |
PROCESS FOR THE SPECIFIC ISOTOPIC LABELING OF METHYL GROUPS OF VAL, LEU AND ILE |
| 摘要 |
The invention relates to a process for the specific isotopic labeling of Valine, Leucine and Isoleucine amino acids. The process of the invention uses a 2-alkyl-2-hydroxy-3-oxobutanoic acid in which the alkyl substituent in position 2 is ethyl or methyl. The invention can be used for the analysis of proteins, in particular by NMR.
|
| 申请公布号 |
US2013122598(A1) |
申请公布日期 |
2013.05.16 |
| 申请号 |
US201013520882 |
申请日期 |
2010.01.06 |
| 申请人 |
GANS PIERRE;BOISBOUVIER JEROME;AYALA ISABEL;HAMELIN OLIVIER;COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIESALTERNATIVES;UNIVERSITE JOSEPH FOURIER;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE |
发明人 |
GANS PIERRE;BOISBOUVIER JEROME;AYALA ISABEL;HAMELIN OLIVIER |
| 分类号 |
C07B59/00;C07C59/215 |
主分类号 |
C07B59/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
