发明名称 |
Therapeutic agent for inflammatory bowel disease comprising 2-amino-1,3-propanaediol derivative as active ingredient, and method for treatment of inflammatory bowel disease |
摘要 |
Disclosed is a 2-amino-1,3-propanediol derivative represented by the formula (1) (e.g., 2-amino-2-[4-(3-benzyloxyphenylthio)-2-chlorophenyl]ethyl- 1,3-propanediol hydrochloride), which is a sphingosine-1-phosphate receptor agonist, or a pharmaceutically acceptable salt or solvate thereof. It is found that the derivative, salt or solvate is useful as a therapeutic agent or a prophylactic agent for an inflammatory bowel disease such as Crohn’s disease, Crohn’s disease of large intestine, intestinal Behcet’s disease, ulcerative colitis, hemorrhagic rectal ulcer or pouchitis. |
申请公布号 |
AU2007213194(B9) |
申请公布日期 |
2013.05.16 |
申请号 |
AU20070213194 |
申请日期 |
2007.02.05 |
申请人 |
KYORIN PHARMACEUTICAL CO., LTD. |
发明人 |
NAKAMARU, KOICHI;YASUE, TOKUTAROU;KOJIMA, RYOTARO |
分类号 |
A61K31/137;A61K45/00;A61P1/00;A61P43/00 |
主分类号 |
A61K31/137 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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