发明名称 |
COMBINED USE OF PRAME INHIBITORS AND HDAC INHIBITORS |
摘要 |
The invention relates to the cancer antigen PRAME (PReferentially expressed Antigen in MElanoma) and its use in a method of treatment of a tumour which comprises administering to a subject in need of treatment an effective amount of an inhibitor of PRAME, in combination with a second agent selected from the group of an inhibitor of HDAC (an HDACi) and a retinoid.
|
申请公布号 |
US2013123327(A1) |
申请公布日期 |
2013.05.16 |
申请号 |
US201113045284 |
申请日期 |
2011.03.10 |
申请人 |
BERNARDS RENE;EPPING MIRJAM;WANG LIMING |
发明人 |
BERNARDS RENE;EPPING MIRJAM;WANG LIMING |
分类号 |
A61K31/7088;A61K31/16;A61K31/18;A61K31/203;A61K45/06;A61K48/00;C12N15/113 |
主分类号 |
A61K31/7088 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|