发明名称 |
CRYSTALLINE SALTS OF QUINOLINE COMPOUNDS AND METHODS FOR PREPARING THEM |
摘要 |
A stable solid pharmaceutical composition consisting essentially of an effective amount of a crystalline salt of formula (II) together with an alkaline-reacting component maintaining the pH preferably above 8, or a salt with a divalent metal cation; and at least one pharmaceutical excipient; to said salt of formula (II) being essentially stable during storage at room temperature for a period of at least 3 years. A process for stabilizing the salt of formula (II). A crystalline salt of formula (II) and a process for preparing said salt.
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申请公布号 |
US2013123301(A1) |
申请公布日期 |
2013.05.16 |
申请号 |
US201213669920 |
申请日期 |
2012.11.06 |
申请人 |
ACTIVE BIOTECH AB;ACTIVE BIOTECH AB |
发明人 |
JANSSON KARL;FRISTEDT TOMAS;WANNMAN HANS;BJORK ANDERS |
分类号 |
A61K31/4704 |
主分类号 |
A61K31/4704 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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