发明名称 |
METHODS OF INHIBITING TUMOR GROWTH BY ANTAGONIZING IL-6 RECEPTOR |
摘要 |
The present invention provides methods for inhibiting or attenuating tumor growth in a subject by administering an IL-6 antagonist to the subject. In certain embodiments, the methods of the invention are used to inhibit the growth of an anti-VEGF-resistant tumor in a subject. The IL-6 antagonist may be, e.g., an antibody that specifically binds IL-6R. The IL-6 antagonist may be administered in combination with a VEGF antagonist, and/or an EGFR antagonist.
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申请公布号 |
US2013122003(A1) |
申请公布日期 |
2013.05.16 |
申请号 |
US201213672923 |
申请日期 |
2012.11.09 |
申请人 |
REGENERON PHARMACEUTICALS, INC.;REGENERON PHARMACEUTICALS, INC. |
发明人 |
ZHANG LI |
分类号 |
C07K16/28;A61K39/395;C07K19/00 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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