发明名称 |
A METHOD FOR DETERMINING THE PROPENSITY FOR CALCIFICATION |
摘要 |
The present invention relates to a method for determining the propensity of a fluid for calcification characterized by the following steps: (i) adding a soluble calcium salt and a soluble phosphate salt to a sample of said fluid; (ii) incubating said sample at conditions allowing the formation of calciprotein particles (CPPs); and (iii) determining one or more of the following:(a) the rate of the formation of primary and/or secondary CPPs; (b) the amount of primary and/or secondary CPPs; and/or (c) the rate of the transition of primary CPPs into secondary CPPs, wherein an increase in one or more of (a), (b) and/or (c) of step (iii) indicates an increased propensity of said fluid for calcification. |
申请公布号 |
WO2013068372(A1) |
申请公布日期 |
2013.05.16 |
申请号 |
WO2012EP71971 |
申请日期 |
2012.11.07 |
申请人 |
RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN |
发明人 |
JAHNEN-DECHENT, WILHELM;PASCH, ANDREAS;FARESE, STEFAN;GRAEBER, STEFFEN |
分类号 |
G01N33/84 |
主分类号 |
G01N33/84 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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