| 摘要 |
A metal coordination complex of a biologically active moiety and a metal is disclosed. The complex confers to the biologically active moeity an improved performance which can include potency, stability, absorbability, targeted delivery, and combinations thereof. WO 2007/050181 PCTfUS2006/031757 Base O ,OR O- z0 Mg 0 -* // R = Rest of RNA molecule Base = Purine or pyrimidine Inner sphere RNA:Magnesium Coordination Complex |
