发明名称 METHOD OF PREPARING 3,3,5,5-TETRAMETHYLCYCLOHEXANONE
摘要 Method of preparing 3,3,5,5-tetramethylcyclohexanone comprising step (i): (i) converting isophorone to 3,3,5,5-tetramethylcyclohexanone in the presence of methylmagnesium chloride. The thus prepared 3,3,5,5-tetramethylcyclohexanone may be employed in a method of preparing 1-amino-1,3,3,5,5-pentamethylcyclohexane (Neramexane) or a pharmaceutically acceptable salt thereof.
申请公布号 US2013123541(A1) 申请公布日期 2013.05.16
申请号 US201013378773 申请日期 2010.06.28
申请人 KOLLER HERBERT;PYERIN MICHAEL;SBROGIO FEDERICO;MERZ PHARMA GMBH & CO. KGAA 发明人 KOLLER HERBERT;PYERIN MICHAEL;SBROGIO FEDERICO
分类号 C07C45/69;C07C209/62 主分类号 C07C45/69
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