发明名称 |
SERS, FLUORESCENCE, ABSORPTION, AND LUMINESCENCE DETECTION WITH FLOW-THROUGH MULTI-HOLE CAPILLARIES |
摘要 |
3-dimensional surface-enhanced Raman scattering (SERS), as well as absorption/fluorescence/luminescence detection is carried out using a platform based on nanoparticle-functionalized flow-through multi-hole capillaries for rapid analyte detection. The configuration provides an increased active area and fluidic channels for efficient sample delivery, and also confines and transmits light for a large signal accumulation. Using a capillary consisting of thousands of micron-sized holes adsorbed with gold nanoparticles, a detection limit better than 100 fM is achieved. |
申请公布号 |
WO2013070948(A1) |
申请公布日期 |
2013.05.16 |
申请号 |
WO2012US64200 |
申请日期 |
2012.11.08 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN |
发明人 |
FAN, XUDONG;GUO, YUNBO;OO, MAUNG KYAW KHAING |
分类号 |
G01N21/65;G01N21/31;G01N21/64 |
主分类号 |
G01N21/65 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|