发明名称 |
PEPTIDES FOR THE REGULATION OF NEUROTRANSMITTER SEQUESTRATION AND RELEASE |
摘要 |
A method of selecting an agent comprising a neuroprotecting activity is disclosed. The method comprises: (a) introducing a plurality of agents into a plurality of cells; and (b) analyzing Vesicular Monoamine Transporter 2 (VMAT2) transcription in the cells; and (c) identifying an agent of the plurality of agents capable of up-regulating DJ-1-dependent VMAT2 transcription in the cells, thereby selecting the agent comprising the neuroprotecting activity.
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申请公布号 |
US2013123187(A1) |
申请公布日期 |
2013.05.16 |
申请号 |
US201213662697 |
申请日期 |
2012.10.29 |
申请人 |
RAMOT AT TEL-AVIV UNIVERSITY LTD.;RAMOT AT TEL-AVIV UNIVERSITY LTD. |
发明人 |
LEV NIRIT;OFFEN DANIEL;MELAMED ELDAD |
分类号 |
C07K7/06;C07K5/103;C07K5/11;C07K5/113;C07K5/117;C07K7/08;C07K14/47;C12Q1/02 |
主分类号 |
C07K7/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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