DENTAL CARE PRODUCTS CONTAINING BIOMIMETIC HYDROXYAPATITE PARTICLES HAVING A LACTOFERRIN-FUNCTIONALIZED SURFACE

摘要

A dental care product comprising carbonate- substituted strontium-hydroxyapatite particles having a lactoferrin-functionalized surface, wherein said particles have the formula: Ca(10-x) Srx (RhoO4)(6-gamma) (CO3)y (OH)2 wherein x is a number comprised between 0.0010 and 0.015; and y is a number comprised between 0.0010 and 0.010; and wherein said carbonate-substituted strontium-hydroxyapatite particles have a crystallinity degree CD comprised between 55 and 85%. The carbonate-substituted strontium-hydroxyapatite particles are biomimetic for composition, structure and morphology allowing a strong chemical affinity with natural enamel and dentine hydroxyapatite crystals and inducing the formation of a rimineralizing and protective surface coating on enamel and dentine.