发明名称 |
ANTI-HUMAN UROTHELIAL CARCINOMA OF SUPERCRITICAL CARBON DIOXIDE EXTRACT OF CINNAMOMUM SUBAVENIUM, AND THE PREPARATION PROCESS AND USES |
摘要 |
What is disclosed in the invention is a preparation method of a supercritical Cinnamomum subavenium extract, which is made from the material, the dried stem of C. subavenium. The extract is obtained by extracting C. subavenium which is pulverized as particles with supercritical carbon dioxide fluid. The C. subavenium extract or its active ingredient, subamolide A, can be used to inhibit the growth of human urothelial carcinoma cell lines. In addition, the C. subavenium extract (or subamolide A) is able to synergistically inhibit the growth of human urothelial carcinoma cell lines with cisplatin (CDDP) or gemcitabine (Gem). Therefore, the C. subavenium extract (or subamolide A) can be an anticancer drug alone, or forms a pharmaceutical composition with CDDP (or Gem) to treat with cancers in respect of urinary system.
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申请公布号 |
US2013122110(A1) |
申请公布日期 |
2013.05.16 |
申请号 |
US201213426136 |
申请日期 |
2012.03.21 |
申请人 |
LI JIH-HENG;HUANG A-MEI;CHEN CHUNG-YI;LIEN PEI-JUNG;LIU CHIUNG-HUI;KAOHSIUNG MEDICAL UNIVERSITY |
发明人 |
LI JIH-HENG;HUANG A-MEI;CHEN CHUNG-YI;LIEN PEI-JUNG;LIU CHIUNG-HUI |
分类号 |
A61K31/341;A61K31/575;A61K31/7068;A61K31/7072;A61K31/7076;A61K31/708;A61K33/24;A61P35/00;C07D305/12 |
主分类号 |
A61K31/341 |
代理机构 |
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代理人 |
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地址 |
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