发明名称 GRAMICIDIN A MUTANTS THAT FUNCTION AS ANTIBIOTICS WITH IMPROVED SOLUBILITY AND REDUCED TOXICITY
摘要 Described herein are antimicrobial peptides for use in pharmaceutical antibiotic compositions and methods of use thereof. These antimicrobial peptides are Gramicidin A (gA) peptide analogs that, in addition to having potent anti-microbial activity, have greatly increased solubility and significantly reduced toxicity in comparison to the wild-type Gramicidin A peptide.
申请公布号 WO2013071049(A1) 申请公布日期 2013.05.16
申请号 WO2012US64364 申请日期 2012.11.09
申请人 TRUSTEES OF BOSTON COLLEGE 发明人 GAO, JIANMIN;WANG, FANG
分类号 A61K38/10;C07K7/28 主分类号 A61K38/10
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