| 发明名称 |
FACTOR VIII T CELL EPITOPE VARIANTS HAVING REDUCED IMMUNOGENICITY |
| 摘要 |
Provided herein are methods and compositions for preventing or reducing an initial immune response to factor VIII in patients suffering from hemophilia A, and for reducing the intensity of the immune response in patients having pre-formed inhibitor antibodies against factor VIII. |
| 申请公布号 |
EP2498803(A4) |
申请公布日期 |
2013.05.15 |
| 申请号 |
EP20100830866 |
申请日期 |
2010.11.15 |
| 申请人 |
PUGET SOUND BLOOD CENTER |
发明人 |
PRATT, KATHLEEN;ETTINGER, RUTH;JAMES, EDDIE. ARTHUR. |
| 分类号 |
A61K38/37 |
主分类号 |
A61K38/37 |
| 代理机构 |
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