A topical pharmaceutical formulation comprising 0.5 ppm to 1000 ppm of a tertiary amine oxide of general formula I. The tertiary amine oxide functions as a preservative or enhances the preservative efficacy in such formulations developed for topical administration. In particular, the topical formulation is an ophthalmic composition.
申请公布号
EP2591780(A1)
申请公布日期
2013.05.15
申请号
EP20130154095
申请日期
2009.10.06
申请人
BAUSCH & LOMB INCORPORATED
发明人
MARLOWE, ZORA TERESA;BANDYOPADHYAY, PARAMITA;WANG, HONGNA;PHILLIPS, ERIC