发明名称 |
Methods and apparatus for fractionation-based chemical analyses |
摘要 |
A method for analyzing chemicals includes fractionating a complex sample into at least two sample portions that each include portions of two polypeptides though in different concentration ratios, digesting and performing LC/MS on each of the sample portions, and associating precursor ions observed via LC/MS with their corresponding polypeptide in response to LC/MS-provided intensity data. A set of precursor-ions that has substantially similar intensity ratios in both sample portions is determined to be associated with the same polypeptide. |
申请公布号 |
US8440465(B2) |
申请公布日期 |
2013.05.14 |
申请号 |
US201213404353 |
申请日期 |
2012.02.24 |
申请人 |
GORENSTEIN MARC V.;GEROMANOS SCOTT J.;SILVA JEFFREY CRUZ;LI GUO-ZHONG;WATERS TECHNOLOGIES CORPORATION |
发明人 |
GORENSTEIN MARC V.;GEROMANOS SCOTT J.;SILVA JEFFREY CRUZ;LI GUO-ZHONG |
分类号 |
G01N33/00 |
主分类号 |
G01N33/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|