| 发明名称 |
Constitutively activated human G protein coupled receptors |
| 摘要 |
The invention disclosed in this patent document relates to transmembrane receptors, more particularly to a human G protein-coupled receptor for which the endogenous ligand is unknown ("orphan GPCR receptors"), and most particularly to mutated (non-endogenous) versions of the human GPCRs for evidence of constitutive activity. |
| 申请公布号 |
US8440391(B2) |
申请公布日期 |
2013.05.14 |
| 申请号 |
US20030723955 |
申请日期 |
2003.11.26 |
| 申请人 |
CHEN RUOPING;LIAW CHEN W.;LOWITZ KEVIN P.;CHALMERS DEREK T.;BEHAN DOMINIC P.;ARENA PHAMACEUTICALS, INC. |
发明人 |
CHEN RUOPING;LIAW CHEN W.;LOWITZ KEVIN P.;CHALMERS DEREK T.;BEHAN DOMINIC P. |
| 分类号 |
C12Q1/00;A61K38/00;C07K14/435;C07K14/705;C07K14/72;C12Q1/68;G01N33/566 |
主分类号 |
C12Q1/00 |
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