发明名称 |
3-substituted-1,4-diazepan-2-one melanocortin-5 receptor antagonists |
摘要 |
The present invention provides compounds of Formula (I) that are useful for modulating the biological activity of the melanocortin-5 receptor (MC5R). Compounds of this invention can be used to treat diseases and/or conditions in which downregulation of MC5R is beneficial. Such diseases and/or conditions include, but are not limited to, acne, seborrhea, seborrheic dermatitis, cancer, and inflammatory diseases. |
申请公布号 |
US8440653(B2) |
申请公布日期 |
2013.05.14 |
申请号 |
US20090919973 |
申请日期 |
2009.02.27 |
申请人 |
BLASKOVICH MARK ARNOLD THOMAS;CASSIDY PETER JOSEPH;MIMETICA PTY LTD |
发明人 |
BLASKOVICH MARK ARNOLD THOMAS;CASSIDY PETER JOSEPH |
分类号 |
C07D243/08;A61K31/551;C07D401/06;C07D401/12 |
主分类号 |
C07D243/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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