发明名称 CELL MEMBRANE PERMEABLE BORON PEPTIDE
摘要 <P>PROBLEM TO BE SOLVED: To provide a cell membrane permeable boron formulation permeating a cell membrane and localized in a cell, especially in a nucleus. <P>SOLUTION: The cell membrane permeable boron peptide includes a cell membrane permeable peptide and a boron compound. The cell membrane permeable peptide has an amino acid sequence of, for example, consecutive 9-13 residues of TAT or arginine, and the boron compound may be, for example, mercapto undecahydrodedecaborate. The cell membrane permeable boron peptide including the cell membrane permeable peptide and the boron compound can be combined with at least one pharmacologically acceptable excipient to produce the boron formulation. <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP2013087098(A) 申请公布日期 2013.05.13
申请号 JP20110230059 申请日期 2011.10.19
申请人 OKAYAMA UNIV 发明人 MICHIUE HIROYUKI;MATSUI HIDEKI;KITAMATSU MIZUO;WANG FEIFEI;TOMIZAWA KAZUHITO
分类号 C07F5/05;A61K38/00;A61P35/00;C07K7/06;C07K7/08;C07K14/005;C07K14/16;C07K14/18;C07K14/39 主分类号 C07F5/05
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