| 摘要 |
Provided in the present invention is a GLP-1 derivate DLG3312 with the structure X-Y-X, wherein the sequence represented by X is H-X8-EGTFTSDVSSYLEGQAAKEFIAWLVKGRG, X8 is any one of A,G,dA or V, and Y represents diaminocarboxylic acid comprising Lys and Om. Also provided in the present invention are the solid-phase chemical synthesis method of the GLP-1 derivate DLG3312 and the use thereof in preparing a drug for treatment of diabetes.
|
| 申请人 |
EAST CHINA NORMAL UNIVERSITY;LAO, XUN;WU, ZIRONG;HUANG, JING;ZHAO, LIFEN;LI, JUAN;ZHAO, YUN;GENG, XU;WANG, ZHENGHUA |
发明人 |
LAO, XUN;WU, ZIRONG;HUANG, JING;ZHAO, LIFEN;LI, JUAN;ZHAO, YUN;GENG, XU;WANG, ZHENGHUA |
