APPARATUS AND METHOD FOR DETERMINING SEQUENCES OF NUCLEIC ACIDS USING ATOMIC FORCE MICROSCOPE

摘要

The present invention relates to an apparatus for determining sequences of nucleic acids using AFM (Atomic Force Microscope) capable of increasing a polymerization speed of a target nucleic acid molecule and enhancing accuracy of analysis through polymerization reaction, and a method using the apparatus, where the apparatus includes a polymerase attached to a tip of a cantilever for the AFM, and a substrate attached by a dNTP, and where the polymerase is moved on a substrate.