COSMETIC COMPOSITIONS OR PHARMACEUTICAL COMPOSITIONS COMPRISING COLLAGEN TYPE I INDUCING FACTOR ISOLATED FROM TRICHINELLA SPIRALIS

摘要

PURPOSE: A cosmetic composition or a pharmaceutical composition containing a type 1 collagen inducing factor isolated from Trichinella spiralis is provided to enhance type 1 collagen synthesis in a tissue and to ensure anti-wrinkling, anti-aging, and wound healing. CONSTITUTION: A cosmetic composition for anti-wrinkling or anti-aging contains type I collagen inducing factor(C1IF) of Trichinella spiralis as an active ingredient. A pharmaceutical composition for wound healing contains C1IF and a pharmaceutically acceptable excipient. [Reference numerals] (AA) Gene expression rate of relative collagen I; (BB,DD,FF,HH,JJ,LL) 28 days; (CC) Gene expression rate of relative collagen II; (EE) Gene expression rate of relative collagen III; (GG) Gene expression rate of relative TGF-βI; (II) Gene expression rate of relative TGF-βII; (KK) Gene expression rate of relative TGF-βIII