摘要 |
The present invention provides a process for purification of diacerein, compound of Formula I, the process comprising a. reacting diacerein, compound of Formula I with a silylating agent to form a compound of Formula II, silylated diacerein wherein R is alkyl; and [Formula (I)] [Formula (II)] b. deprotecting compound of Formula II, silylated diacerein in presence of a polar solvent. |
申请人 |
GLENMARK GENERICS LIMITED;GHARPURE, MILIND;RANE, DNYANDEV;SHUKLA, MANISH CHANDRAKANT;PATIL, PRAMOD VITTHAL;PATLE, GIRISH TILAKCHAND;LAD, SACHIN MAHADEO;BAVISKAR, DEEPAK B. |
发明人 |
GHARPURE, MILIND;RANE, DNYANDEV;SHUKLA, MANISH CHANDRAKANT;PATIL, PRAMOD VITTHAL;PATLE, GIRISH TILAKCHAND;LAD, SACHIN MAHADEO;BAVISKAR, DEEPAK B. |