COMPLEX AGENT CONTAINING CLOPIDOGREL AND ASPIRIN

摘要

The present invention relates to a complex agent of clopidogrel and aspirin, and more particularly, to a complex agent including a capsule containing a granule obtained by coating a clopidogrel layer with a layer for preventing rapid release, and an aspirin granule obtained by coating an aspirin layer with a enteric layer. The physical contact between the clopidogrel and the aspirin may be blocked, and the eutectic phenomenon may be fundamentally blocked. In the short term, a change in the amount, elution properties, and bioequivalence of the agent may be prevented, and in the long term, the stability of the agent may be ensured. In addition, damage to the stomach wall may be prevented by coating the aspirin with the enteric layer.