发明名称 |
COMPOUNDS AND METHODS TO INHIBIT HISTONE DEACETYLASE (HDAC) ENZYMES |
摘要 |
The invention relates to compounds that inhibit histone deacetylase (HDAC) enzymes, the preparation of these compounds, the use of these compounds in the treatment of diseases or conditions ameliorated by inhibition of HDAC activity, and pharmaceutical compositions comprising these compounds. Specifically, the invention relates to compounds having the formula (I), wherein A, X, Y, R, and B are as defined herein, and methods of making and using the same.
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申请公布号 |
WO2013066833(A1) |
申请公布日期 |
2013.05.10 |
申请号 |
WO2012US62507 |
申请日期 |
2012.10.30 |
申请人 |
GLAXOSMITHKLINE LLC;TEMPERO PHARMACEUTICALS, INC.;GHOSH, SHOMIR;LOBERA, MERCEDES;TRUMP, RYAN, PAUL;ZHANG, CUNYU |
发明人 |
GHOSH, SHOMIR;LOBERA, MERCEDES;TRUMP, RYAN, PAUL;ZHANG, CUNYU |
分类号 |
A61K31/4245;C07D271/06;C07D413/10;C07D413/12 |
主分类号 |
A61K31/4245 |
代理机构 |
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代理人 |
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地址 |
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