发明名称 |
ANALYZING CHEMICAL AND BIOLOGICAL SUBSTANCES USING NANO-STRUCTURE BASED SPECTRAL SENSING |
摘要 |
An integrated chromatography-immunoassay system for integrated chromatography-immunoassay system includes a chromatographic unit that receives labeled nano-structured probes comprising nano particles and antibodies attached to the nano particles, and a test membrane comprising coating antigens. The chromatographic unit allows the labeled nano-structured probes to diffuse there through and into the test membrane, wherein the antibodies on the nano particles are bound to the coating antigens. A laser device emits a laser light to illuminate the labeled nano-structured probes having the antibodies bound to the coating antigens on the test membrane. A spectral analyzer obtains a Raman spectrum from light scattered from the labeled nano-structured probes having the antibodies bound to the coating antigens on the test membrane, and to identify a spectral signature in the Raman spectrum associated with the antibody-antigen pair, which enables detection and identification of the antibody.
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申请公布号 |
US2013115717(A1) |
申请公布日期 |
2013.05.09 |
申请号 |
US201213724619 |
申请日期 |
2012.12.21 |
申请人 |
OPTOTRACE (SUZHOU) TECHNOLOGIES, INC.;OPTOTRACE (SUZHOU) TECHNOLOGIES, INC. |
发明人 |
GUO XUN;LIU CHUNWEI;DENG ANPING;CHANG HUAFANG;WANG HONG |
分类号 |
G01N33/543 |
主分类号 |
G01N33/543 |
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地址 |
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