发明名称 |
INDOLEALKYLAMINO-WITHASTEROID CONJUGATES AND METHOD OF USE |
摘要 |
A group of indolealkylamino-withasteroid conjugates, isolated and purified from Withania somnifera, are described. A synthetic method of making an indolealkylamino-withasteroid compound is provided. In vitro acetyl cholinesterase inhibitory activity and methods for treatment of dementia and dementia-related disorders, such as Alzheimer's disease, and anxiety and depressive disorders in mammals are demonstrated with these novel compositions.
|
申请公布号 |
US2013115316(A1) |
申请公布日期 |
2013.05.09 |
申请号 |
US201213669207 |
申请日期 |
2012.11.05 |
申请人 |
NATREON, INC.;NATREON, INC. |
发明人 |
GHOSAL SHIBNATH;VEERARAGAVAN MURUGANANDAM;KALIDINDI SANYASI R. |
分类号 |
A61K31/585;C07J19/00 |
主分类号 |
A61K31/585 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|