发明名称 |
Modulation of the Interaction between SorLA and GDNF-Family Ligand Receptors |
摘要 |
The present invention relates to a method to increase the survival of neurons by modulating the interaction between SorLA and GDNF-family ligand receptors. The agent used to modulate the interaction between the SorLA and GDNF-family ligand receptors are selected from proteins, peptides, antibodies or small organic compounds. The invention also relates to a pharmaceutical compositions comprising these agent as well as the use of said agent or pharmaceutical composition in the treatment of a disease associated with the loss of neurons and/or wherein the survival of neurons are desired.
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申请公布号 |
US2013115212(A1) |
申请公布日期 |
2013.05.09 |
申请号 |
US201113702692 |
申请日期 |
2011.06.14 |
申请人 |
NYKJAER ANDERS;GLERUP SIMON;MADSEN PEDER SOENDERGAARD;PETERSEN CLAUS MUNCK;OLSEN DITTE;LUNDBECK A/S |
发明人 |
NYKJAER ANDERS;GLERUP SIMON;MADSEN PEDER SOENDERGAARD;PETERSEN CLAUS MUNCK;OLSEN DITTE |
分类号 |
A61K39/395 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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