发明名称 |
TARGETED NON-INVASIVE IMAGING PROBES OF EGFR EXPRESSING CELLS |
摘要 |
A probe for imaging EGFR expressing cells includes an EGFR targeting moiety, a reporter moiety, and a hydrophilic linker that links the EGFR targeting moiety to the reporter moiety. The hydrophilic linker enhances solubility of the probe in an aqueous media as well as binding affinity of the probe to EGFR expressing cells.
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申请公布号 |
US2013116404(A1) |
申请公布日期 |
2013.05.09 |
申请号 |
US201213671957 |
申请日期 |
2012.11.08 |
申请人 |
CASE WESTERN RESERVE UNIVERSITY;CASE WESTERN RESERVE UNIVERSITY |
发明人 |
BASILION JAMES;AGNES RICHARD |
分类号 |
C07K7/08;C07K7/56 |
主分类号 |
C07K7/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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