| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide injectable compositions comprising biocompatible, swellable, substantially hydrophilic, non-toxic and substantially spherical polymeric material carriers which are capable of efficiently delivering bioactive therapeutic factor(s) for use in embolization drug therapy. <P>SOLUTION: Substantially spherical microspheres suitable for active embolization includes (a) biocompatible and hydrophobic polymers including vinyl alcohol polymers, poly(lactic acid), polyacrylamides, poly(anhydrides), polysaccharides, silicones, or mixtures thereof, and (b) antineoplastic agents. Furthermore, embolization gene therapy for the treatment of especially neovascular and angiogenesis-dependent diseases uses the injectable compositions. <P>COPYRIGHT: (C)2013,JPO&INPIT |
