| 发明名称 |
NOVEL TETRAHYDROQUINOLINE DERIVATIVES |
| 摘要 |
<p>A compound of formula (I) or a pharmaceutically acceptable salt or ester thereof, wherein A1 to A3 and R1 to R10 have the significance given in claim 1, can be used as a medicament. These compounds are useful in the treatment or prophylaxis of diseases that are related to AMPK regulation, such as obesity, dyslipidemia, hyperglycemia, type 1 or type 2 diabetes and cancers.</p> |
| 申请公布号 |
EP2588458(A1) |
申请公布日期 |
2013.05.08 |
| 申请号 |
EP20110730935 |
申请日期 |
2011.06.29 |
| 申请人 |
F.HOFFMANN-LA ROCHE AG |
发明人 |
CHEN, LI;FENG, LICHUN;HE, YUN;HUANG, MENGWEI;LIU, YONGFU;YUN, HONGYING;ZHOU, MINGWEI |
| 分类号 |
C07D215/48;A61K31/4375;A61K31/47;A61K31/4709;A61P3/04;A61P3/06;A61P3/10;A61P35/00;C07D401/06;C07D405/12;C07D471/04 |
主分类号 |
C07D215/48 |
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