| 发明名称 |
FKBP subtype-specific rapamycin analogue for use in treatment of diseases |
| 摘要 |
<p>The present invention is directed to a FKBP subtype-specific rapamycin analogue selective for a single FKBP, wherein the FKBP subtype-specific rapamycin analogue preferentially forms a complex with only a single FKBP and this complex binds and/or inhibits the mammalian target of rapamycin for use in treatment of cancer, depression, neurodegeneration, transplant rejection or metabolic disorders.</p> |
| 申请公布号 |
EP2589383(A1) |
申请公布日期 |
2013.05.08 |
| 申请号 |
EP20110075245 |
申请日期 |
2011.11.06 |
| 申请人 |
MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. |
发明人 |
HAUSCH, FELIX;MAERZ, ANDREAS M.;BRACHER, ANDREAS. |
| 分类号 |
A61K31/436;A61P3/04;A61P3/10;A61P5/50;A61P7/02;A61P25/00;A61P25/24;A61P25/28;A61P35/00;A61P37/06 |
主分类号 |
A61K31/436 |
| 代理机构 |
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代理人 |
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