发明名称 HYDROGEL WITH IMPROVED TISSUE ADHESION PREVENTION
摘要 PURPOSE: Hydrogel is provided to have improved tissue adhesion inhibition power, and to perform a simple procedure by injection as the hydrogel is in a sol state at room temperature. CONSTITUTION: Hydrogel is manufactured by the cross-link reaction of the following: 100 parts by weight of modified polyethylene-polypropylene-polyethylene copolymer in which one end is substituted with lactic acid and the other end is substituted with ethylene glycol; 1-2 parts by weight of complex cross-linking agents in which more than two kinds of cross-linking agents selected from hyaluronic acid, adipic acid dihydrazid, and sodium alginate are combined; and 0.1-1 parts by weight of more than one divalent metal compound selected from the group consisting of calcium, magnesium, barium, zinc, strontium, and iron(II). The copolymer has the content of lactic acid of 4-7 mol%, and the content of ethylene glycol of 3-6 mol%.
申请公布号 KR101262321(B1) 申请公布日期 2013.05.08
申请号 KR20120137511 申请日期 2012.11.30
申请人 CHOI, MYUNG 发明人 KIM, SANG JIN;CHOI, MYUNG;KIM, JEOUNG YONG
分类号 A61K9/06;A61K47/02;A61K47/30;A61K47/38 主分类号 A61K9/06
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