发明名称 |
Heterocyclic derivatives binding to the peripheral-type benzodiazepine receptor (PBR) |
摘要 |
The present invention relates to quinazoline derivatives as well as multimeric derivatives, methods for their preparation, pharmaceutical compositions including such compounds, and methods of using these compounds for the treatment and prevention of brain damage resulting from brain injury, especially secondary brain damage due to traumatic brain injury (TBI). The compounds of the invention are also useful in treating and preventing neurodegenerative diseases. |
申请公布号 |
EP2589597(A2) |
申请公布日期 |
2013.05.08 |
申请号 |
EP20120176068 |
申请日期 |
2006.08.22 |
申请人 |
TECHNION RESEARCH & DEVELOPMENT FOUNDATION |
发明人 |
GAVISH, MOSHE;VEENMAN, JEHUDA ARIEH;SHTERENBERG, ALEX;MAREK, ILAN |
分类号 |
C07D239/90;A61K31/505;A61P25/00;C07D239/91 |
主分类号 |
C07D239/90 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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