| 摘要 |
PURPOSE: A capsosiphon fulvescens glycoprotein extract with a liver protection effect and a composition containing the same are provided to suppress liver damage or liver diseases caused by acetaminophen or tetrachloride. CONSTITUTION: A capsosiphon fulvescens glycoprotein extract protects liver damaged by acetaminophen or tetrachloride. A pharmaceutical composition for preventing or treating liver diseases caused by the acetaminophen or the tetrachloride contains the extract as an active ingredient. A health food composition for treating the liver diseases caused by the acetaminophen or the tetrachloride contains the extract as the active ingredient. The extract is prepared using C1-C4 anhydrous or hydrous alcohols, a mixture of the alcohols and water, acetone, ethyl acetate, chloroform, 1,3-butylene glycol, hexane, diethyl ether, butyl acetate, or water. [Reference numerals] (AA) Capsosiphon fulvescens; (BB) Homogenization; (CC) Extraction(80°C, 3hr, 320g/8L); (DD) Centrifugation(5000RPM, 20minutes, 4°C); (EE,MM) Residue; (FF,NN) Upper layer liquid; (GG) 80°C, 3hours, 5L; (HH) Second extraction; (II) 2^nd extraction; (JJ) Add 3 times EtOH; (KK,OO) Concentration; (LL) Filtration; (PP) Lyophilization |
