发明名称 |
Pharmaceutical compositions capable of inducing apoptosis in tumour cells, useful for diagnosis and treatment of B-chronic lymphocytic leukaemia |
摘要 |
The present invention is related to the branch of immunology and particularly with the generation of pharmaceutical compositions comprising a humanized monoclonal antibody recognizing the leukocyte differentiation antigen CD6. Accordingly with that statement, the purpose of this invention is to provide pharmaceutical compositions comprising a humanized anti-CD6 monoclonal antibody for the diagnosis and treatment of Lymphoproliferative Syndromes and particularly the B-Cell Chronic Lymphocytic Leukemia. The essence of the invention consist in the application of a humanized Monoclonal Antibody that recognizes the CD6 antigen, the generation of pharmaceutical compositions comprising that antibody being able to induce apoptosis of malignant cells from B-Cell Chronic Lymphocytic Leukemia patients, reaching a clinical and a histological antitumor efficacy. The field of application of the present invention extends to the Oncology. |
申请公布号 |
US8435521(B2) |
申请公布日期 |
2013.05.07 |
申请号 |
US20070525449 |
申请日期 |
2007.12.24 |
申请人 |
MONTERO CASIMIRO JOSE ENRIQUE;ALONSO RAMIREZ RUBY;PEREZ RODRIGUEZ ROLANDO;CENTRO DE IMMUNOLGIA MOLECULAR |
发明人 |
MONTERO CASIMIRO JOSE ENRIQUE;ALONSO RAMIREZ RUBY;PEREZ RODRIGUEZ ROLANDO |
分类号 |
A61K39/395 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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