发明名称 |
Spider silk fusion protein structures for binding to an organic target |
摘要 |
<p>A protein structure capable of selective interaction with an organic target is provided. The protein structure is a polymer comprising as a repeating structural unit a recombinant fusion protein that is capable of selective interaction with the organic target. The fusion protein is comprising the moieties B, REP and CT, and optionally NT. B is a non-spidroin moiety of more than 30 amino acid residues, which provides the capacity of selective interaction with the organic target. REP is a moiety of from 70 to 300 amino acid residues and is derived from the repetitive fragment of a spider silk protein. CT is a moiety of from 70 to 120 amino acid residues and is derived from the C-terminal fragment of a spider silk protein. NT is an optional moiety of from 100 to 160 amino acid residues and is derived from the N-terminal fragment of a spider silk protein. The fusion protein and protein structure thereof is useful as an affinity medium and a cell scaffold material.</p> |
申请公布号 |
AU2011322657(A1) |
申请公布日期 |
2013.05.02 |
申请号 |
AU20110322657 |
申请日期 |
2011.10.25 |
申请人 |
SPIBER TECHNOLOGIES AB |
发明人 |
HEDHAMMAR, MY;JOHANSSON, JAN;RISING, ANNA;NYGREN, PER-AKE |
分类号 |
C07K16/06;A61K47/48;B01D15/38;C07K14/435 |
主分类号 |
C07K16/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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