发明名称 GENERATION AND PROFILING OF FULLY HUMAN HuCAL GOLD-DERIVED THERAPEUTIC ANTIBODY SPECIFIC FOR HUMAN CD38
摘要 <P>PROBLEM TO BE SOLVED: To provide antibodies that are specific to or have a high affinity for CD38 and therapeutic and detection methods using the antibodies. <P>SOLUTION: Uses of an isolated antibody or a functional fragment thereof specific for CD38 is provided, wherein the isolated antibody and the functional fragment thereof includes a specific sequence, and a pharmaceutical composition containing the isolated antibody and the functional fragment thereof and a pharmaceutically acceptable carrier or excipient for a pharmaceutical composition is administered to a subject in need thereof. Using this method using the isolated antibody and the functional fragment thereof, hematological diseases such as multiple myeloma can be treated. <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP2013079238(A) 申请公布日期 2013.05.02
申请号 JP20120246686 申请日期 2012.11.08
申请人 MORPHOSYS AG 发明人 TESAR MICHAEL;JAEGER UTE
分类号 A61K39/395;A61P29/00;A61P35/02;A61P37/02;C07K16/28;C12N15/09 主分类号 A61K39/395
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