PATHWAY RECOGNITION ALGORITHM USING DATA INTEGRATION ON GENOMIC MODELS (PARADIGM)
摘要
A patient sample specific dynamic pathway map is constructed on the basis of measured patient data and a probabilistic pathway model that is based on attributes for pathway elements, wherein some attributes for pathway elements are known a priori, where other attributes for the pathway elements are assumed, and where the pathway elements are cross-correlated and assigned an influence level for at least one pathway. Preferred dynamic pathway maps provide context of the measured patient data with respect to a selected reference pathway activity.
申请公布号
WO2013062505(A1)
申请公布日期
2013.05.02
申请号
WO2011US01844
申请日期
2011.10.31
申请人
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;VASKE, CHARLES, J.;BENZ, STEPHEN, C.;STUART, JOSHUA, M.;HAUSSLER, DAVID
发明人
VASKE, CHARLES, J.;BENZ, STEPHEN, C.;STUART, JOSHUA, M.;HAUSSLER, DAVID