| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide an oral pharmaceutical dosage form of an opioid activator buprenorphine for treating pain, that is less prone to diversion and/or abuse in drug substitution therapy. <P>SOLUTION: There is provided an oral pharmaceutical dosage form containing an opioid activator buprenorphine or a pharmaceutically acceptable salt thereof, wherein the oral pharmaceutical dosage form releases the buprenorphine or the pharmaceutically acceptable salt instantly upon oral, or preferably sublingual, application. The dosage form is preferably one releasing substantially all of the buprenorphine or the pharmaceutically acceptable salt within less than two minutes after oral, or preferably sublingual, application. The dosage form preferably has a shape of mucoadhesive film form or wafer form. <P>COPYRIGHT: (C)2013,JPO&INPIT |
